A Guide To Tissue Characterization & Intraplaque Hemorrhage

Existing intravascular ultrasound technology is capable of finding out the degree and distribution of pathologic processes within the wall of the vessel, but it is not very much responsive in distinguishing between certain kinds of tissue. Tissue characterization refers to a set of methods based on computer that makes use of features of the ultrasound signal ahead of fundamental amplitude to help characterize the composition of the tissue of interest.

This method entails quantitative analysis of the ultrasound signals reflected from tissue prior to these signals pass through the processing steps in the ultrasound instrument.

Cardiac Tissue Characterization

Cardiac tissue characterization is a term for an approach in cardiac imaging utilized for the assessment of the myocardial tissue in respect to its inherent properties as opposed to cardiac function, for instance in cine or strain imaging.

In cardiac magnetic resonance imaging, tissue characterization normally consists of the use of several imaging techniques for the evaluation of dissimilar myocardial tissue properties and shows a discrepancy based on the suggestion and the clinical question.

Intraplaque Hemorrhage

When it comes to advanced coronary atherosclerotic lesions, intraplaque hemorrhage is common. The association between the vulnerability of plaque to disruption and hemorrhage may entail the buildup of free cholesterol from erythrocyte membranes.

It is commonly observed in atherosclerotic plaques and is thought to be a result of a crack in the plaque neovasculature. These micro-vessels are fragile for the reason that they are not supported by smooth muscle cells, and there is focal discontinuity in the endothelial lining.

By contributing to the deposition of free cholesterol, macrophage infiltration, and amplification of the necrotic core, the buildup of erythrocyte membranes within an atherosclerotic plaque may stand for a potent atherogenic stimulus. Such factors may add to the possibility of plaque destabilization.

Intraplaque hemorrhage is a common feature of atherosclerotic plaques and is regarded as one of the features that make out complex lesions paving the way for acute ischemic events. The case of intraplaque hemorrhage is most often secondary to crack of neovessels, which have attacked the plaque.

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